Four restaurants on Jupeater regularly book live entertainment, and they're different enough in format that "live music restaurant" undersells the range: an outdoor tiki stage, a strip-mall seafood shack with a nightly band, a neighborhood bar's karaoke night, and a lounge trio at an upscale steakhouse.
Guanabanas has an actual stage built into its open-air layout. Little Moir's Food Shack runs live music nightly despite its no-frills setting. Nieko's Neighborhood Bar is the karaoke-and-comedy-night option rather than a live band. Eddie V's, the newest and most upscale of the four, features a lounge trio in its V Lounge rather than a full band.
Lineups and performance nights change weekly at most of these - if a specific act or night, like Nieko's karaoke, is the reason you're going, it's worth a quick call or a look at the restaurant's own social media before you head out.